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H-89 dihydrochloride esolicaftor [Epub ahead of print] PubMed

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H-89 dihydrochloride esolicaftor [Epub ahead of print] PubMedH 89 is a specific adenylyl cyclase inhibitor (DDA) and a cyclic AMP dependent protein kinase inhibitor. H 89 blocks the action of equine growth hormone on in vitro maturation of equine oocytes. H 89 decreases the gain of excitation contraction coupling and attenuates calcium sparks in the absence of beta adrenergic stimulation. H 89 potentiates adipogenesis in 3T3 L1 cells by activating insulin signaling independently of protein kinase A. Product

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[Epub ahead of print] PubMed PMID: 26815195

ACS Chem Biol

84(5):710-25

HCT-116 (colon)

H-89 dihydrochloride esolicaftor [Epub ahead of print] PubMedH 89 is a specific adenylyl cyclase inhibitor (DDA) and a cyclic AMP dependent protein kinase inhibitor. H 89 blocks the action of equine growth hormone on in vitro maturation of equine oocytes. H 89 decreases the gain of excitation contraction coupling and attenuates calcium sparks in the absence of beta adrenergic stimulation. H 89 potentiates adipogenesis in 3T3 L1 cells by activating insulin signaling independently of protein kinase A. Product

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