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5 Strategies for addressing resistance to gemcitabine 5.1 New drug delivery systems and precision drug delivery In recent years, researchers have developed a variety of new drug delivery systems to optimize the antitumor activity of gemcitabine, which has limitations such as strong hydrophilicity, rapid metabolism in the body, and low intracellular concentration

3.3 Roche / Carmot (Dual GLP-1/GIP Agonists) Deal: In late 2023, Roche acquired Carmot Therapeutics for $2.7B upfront (plus up to $0.4B milestones) ( [33] )

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While they have different functions, both L-carnitine and L-carnosine are naturally occurring compounds found in the human body