WWTR1 Polyclonal Antibody, 20ul Vacuum Aspirator The protein encoded by this

The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development

maintenance

and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy

also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini

WWTR1 Polyclonal Antibody, 20ul Vacuum Aspirator The protein encoded by thisBinds to transcription factors via its WW domain.,The PDZ binding motif is essential for stimulated gene transcription. It localizes the protein into both punctate nuclear foci and plasma membrane associated complexes.,Functions as a transcriptional coactivator.,PTM: Phosphorylated. Phosphorylation results in the inhibition of transcriptional coactivation through YWHAZ mediated nuclear export.,Contains 1 WW domain.,subcellular location: Concentrates