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EP4 Polyclonal Antibody, 50ul Serological Pipets Mutations in this gene caused

SKU: 92222236136

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SEK142.00 SEK175.00

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EP4 Polyclonal Antibody, 50ul Serological Pipets Mutations in this gene causedProstaglandin E receptor 4 encoded by PTGER4 is a member of the G protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase 2 mRNA, and lead to the phosphorylation of glycogen synthase kinase 3. Knockout studies

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Description

Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4)

The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane

T-complex protein 1 subunit zeta encoded by CCT6A is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT)

This family member is most abundant in muscle but is expressed in all tissues

EP4 Polyclonal Antibody, 50ul Serological Pipets Mutations in this gene causedProstaglandin E receptor 4 encoded by PTGER4 is a member of the G protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase 2 mRNA, and lead to the phosphorylation of glycogen synthase kinase 3. Knockout studies

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