Chk1(Phospho Ser317) Polyclonal Antibody, 100ul Thermal Control The main portion of the

The main portion of the receptor is a heterodimer composed of 2 polypeptide chains

and proline-rich C-termini

Alternative splicing at this locus results in different isoforms

The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

Chk1(Phospho Ser317) Polyclonal Antibody, 100ul Thermal Control The main portion of theThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells