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TH(Phospho Ser62) Polyclonal Antibody, 20ul Enzymes endoplasmic reticulum (ER)-associated protein that

SKU: 73483882324

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TH(Phospho Ser62) Polyclonal Antibody, 20ul Enzymes endoplasmic reticulum (ER)-associated protein thatThe protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins

The protein encoded by this gene is a component of the histone deacetylase complex| which includes SIN3| SAP30| HDAC1| HDAC2| RbAp46| RbAp48| and other polypeptides

As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted

or cellular calcium/phosphate homeostasis

TH(Phospho Ser62) Polyclonal Antibody, 20ul Enzymes endoplasmic reticulum (ER)-associated protein thatThe protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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