SIGIR Polyclonal Antibody, 20ul Filtration which indicates a direct link

which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides

induction:By prolactin and androgen

This protein also interacts with transcription factor AP2 (TFAP2)

May play a role in cell proliferation of NT2 embryonal carcinoma cells

SIGIR Polyclonal Antibody, 20ul Filtration which indicates a direct linkActs as a negative regulator of the Toll like and IL 1R receptor signaling pathways. Attenuates the recruitment of receptor proximal signaling components to the TLR4 receptor, probably through an TIR TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,Belongs to the interleukin 1 receptor family.,Contains 1 Ig like C2 type (immunoglobulin like) domain.,Contains 1 TIR