Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration subunit:Oligomerizes and associates with TNKS

subunit:Oligomerizes and associates with TNKS

but their full length sequences have not been determined

Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs

It binds mutliple lipid-containing molecules| including phosphatidylserine| phosphatidylinositol 4-phosphate (PI4P) and oxysterol| and promotes their exchange between the endoplasmic reticulum and the plasma membrane

Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration subunit:Oligomerizes and associates with TNKSThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.