PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody, 100ul Capsule Filter ADAM10 encodes and ADAM family

ADAM10 encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin

Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported| with the most common allele| Ile654/Ile655| shown here

Migrates to the nucleus when complexed with SMAD4

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I)

PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody, 100ul Capsule Filter ADAM10 encodes and ADAM familyThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in