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Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research Transcriptional modulator activated by BMP

SKU: 5877876804

4.7
SEK141.00 SEK174.00

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Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research Transcriptional modulator activated by BMPMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.

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Description

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase

Based on sequence comparison

Mutations in KRT10 are associated with epidermolytic hyperkeratosis

PTM:Several N-termini have been identified by direct sequencing

Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research Transcriptional modulator activated by BMPMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.

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