CD68 Monoclonal Antibody(6F3), 100ul Peptide Modification Three isoforms of cortactin exist

Three isoforms of cortactin exist due to the alternative splicing

Stat5 is activated in response to a wide variety of ligands including IL-2

This protein is regulated by calcium/calmodulin concentration and may be involved in brain development

This protein is known to play a role in regulation of autophagy during cell death

CD68 Monoclonal Antibody(6F3), 100ul Peptide Modification Three isoforms of cortactin existThis gene encodes a 110 kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal endosomal associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue and organ