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FLT3(Phospho-Tyr589/591) Rabbit Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The protein encoded by SELE

SKU: 41156519420

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FLT3(Phospho-Tyr589/591) Rabbit Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The protein encoded by SELEThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis

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Description

The protein encoded by SELE (selectin E) is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining

|subunit:Associates with the SH2 domains of SRC| FYN and ABL

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and it is the ligand for two proteins at the cell surface of T cells

FLT3(Phospho-Tyr589/591) Rabbit Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The protein encoded by SELEThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis

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