Dkk-1 Monoclonal Antibody, 50ul In vitro Assessment including proliferation

including proliferation

The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities

Many alternatively spliced transcript variants exist for this gene

GO annotations related to this gene include poly(A) RNA binding and methylated histone binding

Dkk-1 Monoclonal Antibody, 50ul In vitro Assessment including proliferationThis gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.